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Introduction to Four New Anti Schizophrenic Drugs

Schizophrenia is the most prevalent mental illness, and patients are prone to recurrent attacks, requiring long-term medication maintenance treatment. There are many drugs for treating schizophrenia, and the therapeutic effects of different drugs also vary. Today, I will take you through a list of four new anti schizophrenia drugs.

 

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1. Lumepirone. It combines strong serotonin 2A receptor antagonists, glutamate modulators, and serotonin reuptake inhibitors, while also improving sleep quality and reducing negative symptoms of schizophrenia. It also has certain effects on depression, anxiety, and other symptoms related to impaired social function. Lumepirone will not lead to an increase in the risk of diabetes and cardiovascular disease. Therefore, compared with many existing antipsychotic drugs, it has significantly improved long-term safety and tolerance.

2. Amisulpiride is a sedative alternative to aniline and is currently a relatively new second-generation antipsychotic drug that can improve and control psychiatric symptoms. Clinically, it is mainly used to treat schizophrenia, and small doses can also treat the lazy and numb state of depression. The incidence of serious adverse reactions is less than 3%, indicating high safety.

3. Bretirasazin has a novel mechanism of multimodal regulation of the 5-hydroxytryptamine and dopamine signaling pathways. At present, it can not only treat schizophrenia, but also has certain therapeutic effects on bipolar disorder and depression.

4.ALKD3831, a double-layer tablet. The antipsychotic efficacy is comparable to that of olanzapine, and there are no side effects of weight gain. Overall, the tolerance and safety are good.