Acetylcysteine Effervescent Tablets Reference Listed Drug

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Name	Acetylcysteine Effervescent Tablets
Trade name	Fluimucil
Specifications	0.6g
Dosage form	Tablets (effervescent tablets)
Licensee	ZAMBON ITALIA S.R.L
Remarks	Original research import

Acetylcysteine effervescent tablets are used to treat chronic obstructive pulmonary disease (COPD), chronic bronchitis (CB), emphysema (PE) and other chronic respiratory infections that secrete a lot of thick sputum. The active ingredient of this product is N-acetyl-L-cysteine (NAC), which decomposes mucin complexes and nucleic acids to transform purulent components in sputum and other mucus and mucus secretions from viscous to viscous It is thin and exerts a strong mucus dissolving effect. This product exerts a direct antioxidant effect through a free sulfhydryl group (nucleophilic -SH) that can directly interact with the electrophilic oxidizing group. This product can protect α-1 antitrypsin (elastase inhibitor) from inactivation caused by hypochlorous acid (HOCl). Hypochlorous acid is a strong oxidant produced by activating myeloperoxidase in phagocytes. This product is especially suitable for the treatment of acute and chronic respiratory infections characterized by thick mucus and viscous secretions. The molecular structure of this product makes it easy to penetrate cell membranes. In the cell, this product removes the acetyl group to form L-cysteine, which is an essential amino acid for the synthesis of glutathione (GSH). GSH is a highly active tripeptide widely found in various animal tissues. Glutathione is the most important protective agent in cells, and it is necessary to maintain the integrity of cell function and cell morphology. It can prevent cells from being damaged by natural oxygen free radicals and various cytotoxic substances. This product plays an important role in maintaining proper GSH levels, thereby helping to protect cells from cytotoxic damage caused by low GSH levels in the body, such as acetaminophen poisoning. Due to the mechanism of this action, this product can also be used as a special antidote during paracetamol poisoning, cyclophosphamide treatment and hemorrhagic cystitis (in the latter case, This product provides the sulfhydryl group necessary to inactivate acrolein without interfering with chemotherapy. Acrolein is a toxic metabolite that affects the urinary tract mucosa).

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