Mesalazine Enteric-coated Tablets Reference Listed Drug

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Name	Mesalazine Enteric-coated Tablets
Trade name	Salofalk
Specifications	0.25g
Dosage form	Tablets (enteric-coated tablets)
Licensee	Dr. Falk Pharma GmbH
Remarks	Original research import

Mesalazine is the main active ingredient of sulfasalazine and is used to treat ulcerative colitis. Under the action of bacteria in the colon, sulfasalazine is converted into equivalent molecular numbers of sulfapyridine and mesalazine. The mechanism of action of mesalazine (and sulfasalazine) is unclear, and it may be mainly through local rather than systemic effects. In patients with chronic inflammatory bowel disease, the cyclooxygenase pathway (producing prostaglandins) and lipoxygenase pathway (producing leukotrienes and hydroxyeicosatetraenoic acid) can make local mucosal The production of arachidonic acid metabolites is increased, and mesalazine may reduce the local inflammation by inhibiting the production of cyclooxygenase and prostaglandins in the colon.

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