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Trade name:VASTAREL
Specifications:35mg
Dosage form:Tablets (sustained release tablets)
* Please be kindly noted products are supplied for RLD supplies/ Reference listed drugs/ Comparator Drug Clinical trials. We do not sell to patients.
| Name | Trimetazidine Dihydrochloride Modified Release Tablets |
|---|---|
| Trade name | VASTAREL |
| Specifications | 35mg |
| Dosage form | Tablets (sustained-release tablets) |
| Licensee | LES LABORATOIRES SERVIER |
| Remarks | Listed in the European Union (listed country: France; place of origin: France) |
| Category | Reference Listed Drugs (RLDs) |
1. The mechanism of action of this product: Trimetazidine prevents the decrease of intracellular ATP level by protecting the energy metabolism of cells under hypoxia or ischemia, thereby ensuring the normal function of the ion pump and the permeability of sodium-potassium flow. Normal operation to maintain the stability of the cell environment. Trimetazidine inhibits the β-oxidation of fatty acids by blocking the long-chain 3-ketoacyl-CoA thiolase, thereby promoting glucose oxidation. In ischemic cells, lower oxygen consumption is required to obtain energy through glucose oxidation compared to the β-oxidation process. Enhancing glucose oxidation can optimize the energy process of cells, thereby maintaining proper energy metabolism during ischemia.
2. Pharmacodynamic effects of this product: In patients with ischemic heart disease, trimetazidine as a metabolizing agent can maintain the level of high-energy phosphate in myocardial cells. Realize the effect of anti-myocardial ischemia without affecting hemodynamics.
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We are a global professional manufacturer and supplier of reference drug products, featuring high-quality services and competitive prices. You can get the most favorable reference drug prices here. If you need customized services, please contact us immediately.
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