Famciclovir Tablets Reference Listed Drug

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Name	Famciclovir Tablets
Trade name	Famvir
Specifications	0.125g；0.25g
Dosage form	tablet
Licensee	Novartis Pharmaceuticals UK Limited
Remarks	Listed in EU (Origin: Spain)

This product is rapidly transformed into the compound penciclovir with antiviral activity in the body. The latter is effective against herpes simplex virus type I (HSV-1), herpes simplex virus type II (HSV-2) and varicella-zoster virus (VZV). ) Has an inhibitory effect. In cell culture studies, the inhibitory effect of penciclovir on the following viruses is arranged in the order of HSV-1, HSV-2, VZV. The mechanism of action is as follows: In cells infected with the above viruses, viral thymidine kinase phosphorylates penciclovir into penciclovir monophosphate, which is then converted to penciclovir triphosphate by cellular kinases. In vitro studies have shown that penciclovir triphosphate inhibits the activity of HSV-2 polymerase by competing with guanosine triphosphate, thereby selectively inhibiting herpes virus DNA synthesis and replication.

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