Levodopa And Benserazide Hydrochloride Capsules Reference Listed Drug

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Name	Levodopa and Benserazide Hydrochloride Capsules
Trade name	Madopar
Specifications	Levodopa 100mg, benserazide 25mg (equivalent to benserazide hydrochloride 28.5mg)；Levodopa 200mg, benserazide 50mg (equivalent to benserazide hydrochloride 57mg)
Dosage form	Capsules
Licensee	Roche Products Limited
Remarks	Listed in the European Union (Listing country: UK; Origin: UK)

This product is a compound preparation containing levodopa and benserazide. Benserazide is a peripheral decarboxylase inhibitor, which is not easy to enter the center. It only inhibits the conversion of peripheral levodopa to dopamine, and increases the content of levodopa in the circulation by 5-10 As a result, the amount of levodopa that enters the central nervous system is also increased, and levodopa is converted into dopamine by the action of dopa decarboxylase in the brain to exert pharmacological effects and improve the symptoms of Parkinson's disease. The combination of benserazide and levodopa can not only reduce the adverse effects of levodopa in the peripheral cardiovascular system, but also reduce the dosage of levodopa.

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