Venlafaxine Hydrochloride Sustained-release Tablets Reference Listed Drug

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Name	Venlafaxine Hydrochloride Sustained-release Tablets
Trade name	-
Specifications	37.5mg (calculated as C17H27NO2)；75mg (calculated as C17H27NO2)
Dosage form	Tablets (sustained release tablets)
Licensee	Osmotica Pharmaceutical Corp
Remarks	The Orange Book of the United States (The name of the Orange Book of the United States: Venlafaxine Hydrochloride Extended Release Tablets)

This product is suitable for various types of depression, including depression accompanied by anxiety, and generalized anxiety disorder. Non-clinical studies have shown that venlafaxine and its active metabolite O-desmethylvenlafaxine are strong inhibitors of 5-HT and NE reuptake, and weak inhibitors of dopamine. In vitro experiments have not found that venlafaxine and O-desmethylvenlafaxine have obvious affinity for M choline receptors, H1 histamine receptors, and α1-adrenergic receptors. Venlafaxine and O-desmethylvenlafaxine have no MAO inhibitory activity.

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