Mianserin Hydrochloride Tablets Reference Listed Drug

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Name	Mianserin Hydrochloride Tablets
Trade name	Tetramide
Specifications	30mg
Dosage form	tablet
Licensee	MSD K.K.
Remarks	Japanese Orange Book, the name of the Japanese Orange Book: γ-Aminobutyric Acid Tablets

This product is an antidepressant. It can relieve the symptoms of depression in patients with various types of depression who are treated with drugs. Mianserin hydrochloride tablets are a non-tricyclic antidepressant in chemical structure, and its active ingredient is a piperazine-azepine compound. Since there is no basic side chain of tricyclic antidepressants in its chemical structure, this side chain is considered to be related to the anticholinergic effect of tricyclic antidepressants. Therefore, Mianserin hydrochloride has no anticholinergic side effects. The antidepressant effect of Mianserin hydrochloride is similar to that of other antidepressants currently used, but it also has anti-anxiety effects. Mianserin hydrochloride is well tolerated, especially for elderly patients and patients with cardiovascular disease. Mianserin hydrochloride has no anticholinergic effect and does not produce obvious cardiovascular system reaction at the therapeutic dose. Compared with tricyclic antidepressants, even if an overdose of mianserin hydrochloride is taken, there is little toxic effect on the heart. Mianserin hydrochloride does not antagonize sympathomimetic drugs, does not antagonize hypertension drugs (benzyldimethoxine) or α-receptor blockers (such as clonidine, methyldopa), nor does it affect coumarin resistance. The role of coagulants, such as phenylprocoumarin.

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