Stavudine Capsules Reference Listed Drug

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Name	Stavudine Capsules
Trade name	Zerit
Specifications	15mg；20mg；40mg
Dosage form	Capsules
Licensee	BRISTOL MYERS SQUIBB CO PHARMACEUTICAL RESEARCH INSTITUTE
Remarks	American Orange Book

Stavudine is used in combination with other antiviral drugs to treat type I HIV infection. Clinical medication: Regarding the combination of this product and other antiviral drugs in the treatment of HIV-infected patients, there have been several clinical research results of its dual and triple combination drugs. Among them is a multi-center clinical study numbered STARTl. This open randomized study compared this product (40 mg, BID) plus lamivudine and indinavir, and zidovudine plus lamivudine and indinavir in 202 patients who received treatment for the first time. treatment plan. The results showed that within 48 weeks, whether it was the degree of inhibition of HIV RNA or the increase of CD4 cells, the two treatments had the same effect. From 1992 to 1994, a randomized double-blind study numbered AI455-019 collected 822 cases with a series of HIV-related symptoms, and compared the efficacy of this product and zidovudine. The results showed that the two It has the same effect on the progression and death of HIV disease.

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