Valsartan Tablets Reference Listed Drug

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Name	Valsartan Tablets
Trade name	DIOVAN
Specifications	40mg；80mg；160mg
Dosage form	tablet
Licensee	NOVARTIS PHARMACEUTICALS CORP
Remarks	American Orange Book

Valsartan is an angiotensin Ⅱ (Ang Ⅱ) receptor antagonist, which can selectively block the binding of Ang Ⅱ and AT1 receptor (its specific antagonistic effect on AT1 receptor is about 20,000 times greater than AT2). ^ It inhibits vasoconstriction and the release of aldosterone, resulting in a hypotensive effect. This product does not act on angiotensin-converting enzyme (ACE), renin and other receptors, and does not inhibit ion channels related to blood pressure regulation and sodium balance; this product does not affect the level of bradykinin in the body, resulting in fewer side effects of coughing For angiotensin converting enzyme inhibitors.

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