Glipizide Controlled Tablets Reference Listed Drug

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Name	Glipizide Controlled Tablets
Trade name	Glucotrol XL
Specifications	5mg
Dosage form	Tablets (controlled release tablets)
Licensee	Pfizer Inc.
Remarks	Original research import

This product is suitable for the treatment of hyperglycemia and related symptoms in patients with type 2 diabetes (also known as non-insulin-dependent diabetes NIDDM or adult-onset diabetes) on the basis of adequate diet control. This product is suitable for the treatment of hyperglycemia that cannot be controlled by diet alone. Even if the patient has taken this product, diet control is still very important. A 12-week rigorously controlled study showed that compared with placebo, the average HbA1c of patients treated with this product was reduced by up to 1.7% (absolute value). When starting the treatment of type 2 diabetes, it should be emphasized that diet control is the basic treatment. For obese patients, calories must be restricted to reduce weight. In terms of controlling blood sugar and relieving symptoms of hyperglycemia, appropriate diet therapy may be effective. The importance of routine physical exercise should be emphasized, cardiovascular risk factors should be identified, and appropriate treatment measures should be taken. If the above treatment does not relieve symptoms and/or lower blood sugar, oral sulfonylureas should be considered. If you need to further relieve symptoms and/or lower blood sugar, consider adding insulin therapy. Both doctors and patients should recognize that this product is an additional treatment for diet therapy. It can neither replace diet therapy nor be a convenient way to avoid diet control. In some cases, the failure of diet alone to control blood sugar may be temporary, and glipizide is only needed for short-term treatment. For sulfonylureas, including glipizide controlled-release tablets, for primary failure or secondary failure, this product can be considered in combination with other hypoglycemic drugs. Alternative methods include: using other hypoglycemic drugs or insulin instead of this product. If this product can no longer achieve the effect of lowering blood sugar, stop using it. The efficacy must be judged based on routine clinical and laboratory tests. When considering the use of this product for asymptomatic patients, it should be understood that the control of blood sugar in type 2 diabetic patients has not been confirmed to be effective in preventing long-term cardiovascular and neurological complications in diabetic patients. However, controlling the blood sugar of insulin-dependent diabetes patients can effectively slow down the progression of diabetic retinopathy, nephropathy and neuropathy.

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