2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-Triazol-3-one

Chemical Name	2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-Triazol-3-one
Chinese Name	泊沙康唑主环
CAS. No.	184177-83-1
Molecular Formula	C30H35N5O3
Molecular Weight	513.63 g/mol

 

 

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-Triazol-3-one is an intermediate in the preparation of Posaconazole. It is a second-generation triazole antifungal drug listed on the FDA in 2006. The trade name is NOXAFIL, and the original manufacturer is Schering-Plough.

 

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