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Venlafaxine Hydrochloride Sustained-Release Capsules Reference Listed Drug

Venlafaxine Hydrochloride Sustained-Release Capsules Reference Listed Drug

Trade name:EFEXOR XR
Specifications:75mg (calculated as C17H27NO2)
Dosage form:Capsules (sustained release capsules)
For R&D purposes only.

Product Details

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Name Venlafaxine Hydrochloride Sustained-Release Capsules
Trade name EFEXOR XR
Specifications 75mg (calculated as C17H27NO2)
Dosage form Capsules (sustained release capsules)
Licensee Pfizer Healthcare Ireland
Remarks Original research import



This product is an antidepressant used to treat various types of depression (including depression with anxiety) and generalized anxiety disorder. Non-clinical studies have shown that venlafaxine and its active metabolite O-desmethylvenlafaxine are strong inhibitors of 5-HT and NE reuptake, and weak inhibitors of dopamine. In vitro experiments have not found that venlafaxine and O-desmethylvenlafaxine have obvious affinity for M choline receptors, H1 histamine receptors, and α1-adrenergic receptors. Venlafaxine and O-desmethylvenlafaxine have no MAO inhibitory activity.

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