Tegafur Capsules Reference Listed Drug

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Name	Tegafur Capsules
Trade name	Futraful
Specifications	0.2g
Dosage form	Capsules
Licensee	TAIHO PHARMACEUTICAL CO., LTD.
Remarks	Japanese Orange Book, Japanese market name Salazosulfapyridine Enteric-coated Tablets

【Indications】

 Suitable for gastrointestinal tumors, such as gastric cancer, colon cancer, and pancreatic cancer. It can also be used for breast cancer, bronchial lung cancer and primary liver cancer. 

【Pharmacology】

 This product is a derivative of fluorouracil, which is gradually transformed into fluorouracil by liver activation in the body to play an anti-tumor effect. It interferes with and blocks the synthesis of DNA, RNA and protein in the body. It is an anti-pyrimidine cell cycle specific drug, which mainly acts on the S phase of the cell proliferation cycle, and also has a continuing effect on the G1/S transition phase. The chemotherapy index is twice that of fluorouracil, and the toxicity is only 1/4 to 1/7 of that of fluorouracil.

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