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Reference Listed Drugs
Sulpiride Tablets Reference Listed Drug

Sulpiride Tablets Reference Listed Drug

Trade name:Abilit
Specifications:50mg,100mg
Dosage form:tablet
For R&D purposes only.

Product Details

* Please be kindly noted products are supplied for RLD supplies/ Reference listed drugs/ Comparator Drug Clinical trials. We do not sell to patients.


Name Sulpiride Tablets
Trade name Abilit
Specifications 50mg,100mg
Dosage form tablet
Licensee Dainippon Sumitomo Pharma Co., Ltd.
Remarks Japanese Orange Book, Japanese market name Salazosulfapyridine Enteric-coated Tablets


【Indications】

 It has a good effect on apathy, withdrawal, stupor, depression, hallucinations and delusions. It is suitable for schizophrenia with simple, paranoid, catatonic, and chronic schizophrenia withdrawn, withdrawn, and indifferent. It has a certain effect on depression symptoms. Other uses are anti-vomiting 

【Pharmacology】

 This product is a benzamide/antipsychotic. Its function is to selectively block the dopamine (DA2) receptors in the limbic system of the brain, and has little effect on other transmitter receptors. The anticholinergic effect is lighter. Obviously sedative and anti-irritating action, this product also has strong antiemetic and inhibiting gastric secretion 

【Pharmacokinetics】

 This product is absorbed from the gastrointestinal tract and can reach the peak blood concentration in 2 hours/hour. After taking this product for 48 hours, 30% of the oral dose is excreted in urine, and a part is excreted in feces. The plasma half-life (t1/2) is 8-9 hours. Animal experiments show that this product can enter the cord blood circulation through the placental barrier. This product is mainly excreted through the kidneys. Can be excreted from breast milk





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