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CAS: 518-28-5
Source: United States
Qualifications: -/USDMF/-/-
* Please be kindly noted products are offered for R&D purposes only. Not for human or veterinary use.
| Name | Podophyllotoxin |
| Chinese name | 鬼臼毒素 |
| Cas Number | 518-28-5 |
| Source | United States |
| Qualifications | -/USDMF/-/- |
Podophyllotoxin is a non-alkaloid toxin lignan extracted from the roots and rhizomes of the Podophyllum species. It binds to topoisomerase II during the late S and early G2 stage, blocking tubulin polymerization and, thus, inhibiting mitosis. In addition to being used as a cathartic, purgative, antiviral agent, vesicant, and antihelminthic, podophyllotoxin is the starting material for the semi-synthesis of the anti-cancer drugs etoposide, teniposide, and etopophos.
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