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CAS: 32780-64-6
Source: India
Qualifications: USDMF/-/-/-
| Name | Labetalol HCL |
| Chinese name | 盐酸拉贝洛尔 |
| Cas Number | 32780-64-6 |
| Source | India |
| Qualifications | USDMF/-/-/- |
Labetalol hcl is a selective antagonist for the α1-adrenergic receptor and a non-selective antagonist for the β-adrenergic receptor. Labetalol hcl has been used for the treatment of high blood pressure. It competitively targets the α1-adrenergic receptors expressed in vascular smooth muscle, thus inhibiting adrenergic stimulation on endothelial cells and vasoconstriction in peripheral blood vessels. It also blocks the β-adrenergic receptors in bronchial and vascular smooth muscle to counteract adrenergic stimulation. Ultimately, it causes decreases in resting and exercises heart rates, cardiac output, as well as in both systolic and diastolic blood pressure, exherting vasodilation, as well as negative chronotropic and inotropic cardiac effects.
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