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Name: Terbinafine
Chinese Name: 特比萘芬碱基
CAS. No.: 91161-71-6
Molecular Formula: C21H25N
Molecular Weight: 291.43 g/mol
Source: Europe
Qualifications: -/-/-/-/-
| Name | Terbinafine |
|---|---|
| Chinese Name | 特比萘芬碱基 |
| CAS. No. | 91161-71-6 |
| Molecular Formula | C21H25N |
| Molecular Weight | 291.43 g/mol |
| Source | Europe |
| Qualifications | -/-/-/-/- |
Terbinafine is a second-generation allylamine that is related to naftifine; however, it is 10 to 100 times more potent in vitro. It is fungicidal, whereas griseofulvin, ketoconazole, itraconazole, and other azole derivatives are all fungistatic. Because it is fungicidal, the duration of therapy is shorter, and relapse rates are less than with other oral or topical therapies. Terbinafine acts by inhibiting squalene epoxidase and thereby decreasing the synthesis of ergosterol, an essential component of fungal cell membranes.
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