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Name: Nepafenac
Chinese Name: 奈帕芬胺
CAS. No.: 78281-72-8
Molecular Formula: C15H14N2O2
Molecular Weight: 254.28 g/mol
Source: India
Qualifications: -/-/-/-/-
Name | Nepafenac |
---|---|
Chinese Name | 奈帕芬胺 |
CAS. No. | 78281-72-8 |
Molecular Formula | C15H14N2O2 |
Molecular Weight | 254.28 g/mol |
Source | India |
Qualifications | -/-/-/-/- |
Nepafenac is a new ophthalmic non-steroidal antipyretic analgesic and anti-inflammatory drug. In August 2005, the US FDA allowed its ophthalmic suspension (Alton Company) to be used clinically, making it FDA The first non-hormonal anti-inflammatory prodrug approved for ophthalmic use. Nepafenac can quickly pass through the cornea and be converted into aminophenol acid under the action of tissue hydrolase, which can quickly reach the target site to play a role. EMA also approved the new indication of nepafenac, which can be used to reduce pain and inflammation after cataract surgery in diabetic patients, and reduce the risk of macular edema after cataract surgery in diabetic patients.
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