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Name: Etoricoxib
Chinese Name: 依托考昔
CAS. No.: 202409-33-4
Molecular Formula: C18H15ClN2O2S
Molecular Weight: 358.84 g/mol
| Name | Etoricoxib |
|---|---|
| Chinese Name | 依托考昔 |
| CAS. No. | 202409-33-4 |
| Molecular Formula | C18H15ClN2O2S |
| Molecular Weight | 358.84 g/mol |
Etoricoxib is a kind of highly selective cyclooxygenase-2 (COX-2) inhibitor developed by the Merck company. Etoricoxib has a unique chemical structure that is methylsulfonyl group. The introduction of this group can not only increase the selectivity for COX-2 drugs but also does not produce sulfa drugs and cross-allergic reactions. Etoricoxib was first approved for entering into the market in 2002 in the UK, followed by the marketing countries and regions including the European Union, Asia, Australia, and Latin America. Until the end of 2013, it has been approved for marketing in 97 countries for being widely used in the treatment of osteoarthritis (OA), rheumatoid arthritis, ankylosing spondylitis, chronic low back pain, acute gouty arthritis, primary dysmenorrhea, and postoperative pain, and other diseases. Etoricoxib has also entered into the market in Taiwan and Hong Kong of China. It entered the Chinese mainland market in 2008 with the approved indications being acute gouty arthritis and OA and another indication being primary dysmenorrhea in the second half year of 2014.
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