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Name: Palbociclib
Chinese Name: 帕布昔利布
CAS. No.: 571190-30-2
Molecular Formula: C24H29N7O2
Molecular Weight: 447.53 g/mol
Name | Palbociclib |
---|---|
Chinese Name | 帕布昔利布 |
CAS. No. | 571190-30-2 |
Molecular Formula | C24H29N7O2 |
Molecular Weight | 447.53 g/mol |
Palbociclib was developed by Pfizer. It is a cyclin-dependent kinase (CDK) 4 and CDK6 inhibitor approved by the FDA in 2015 to treat hormone receptor-positive (HR+) human epidural growth factor 2-negative (HER2-) metastatic breast cancer. It is used in combination with letrazole as the first-line hormonal-based therapy in postmenopausal women, or with fulvestrant in women with disease progression following hormonal therapy. Palbociclib was discovered at Warner-Lambert and developed by Pfizer after their merger. Pfizer is also studying the effectiveness of palbociclib in a variety of other cancers at various stages in the clinic.
Storage: It should be kept refrigerated between 2°C to 8°C.
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