Pilocarpine Hydrochloride API

Name	Pilocarpine hydrochloride
Chinese name	盐酸毛果芸香碱
Cas Number	54-71-7
Source	Europe
Qualifications	USDMF/CEP/-/-/-

Pilocarpine is a cholinergic muscarinic agonist with direct action. It has been used for the treatment of chronic open-angle glaucoma and acute angle-closure glaucoma for more than 100 years by directly stimulating the pupillary sphincter, ciliary body and secretory glands. Muscarinic receptors. Studies have shown that pilocarpine hydrochloride has obvious effects of reducing intraocular pressure and controlling inflammation, and can treat primary glaucoma, including open-angle and angle-closure glaucoma. It is the first-line medication for clinical treatment of glaucoma. Compared with physostigmine, pilocarpine has a mild and short-lived effect, and its aqueous solution is more stable. On the basis of conventional treatment, the combined treatment of timolol eye drops and pilocarpine eye drops for patients with primary open-angle and secondary glaucoma can help to further reduce the patient's intraocular pressure level, which is useful for pupil recovery Positive meaning. Another recent study pointed out that pilocarpine can significantly delay the occurrence of ventricular arrhythmia, shorten the duration of ventricular arrhythmia, and reduce the severity of ventricular arrhythmia. In 2016, the sales of ophthalmic drugs in pharmacies in key cities in China reached 1.517 billion yuan, an increase of 17.35% year-on-year. Pilocarpine is the TOP10 drug for glaucoma retail in pharmacies in key cities in China.

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