Procapride API

Name	Procapride
Chinese name	普芦卡必利
Cas Number	179474-81-8
Source	India
Qualifications	USDMF/-/-/-/-

Procapride is a dihydrobenzofuran carboxamide compound. It is a selective, high-affinity serotonin (5-HT4) receptor agonist with intestinal motility activity. It was originally developed by Ipsen Pharmaceuticals (Ipsen ), the drug is currently on the market in 27 countries and regions. As a highly selective serotonin (5-HT) 4 receptor agonist, prucalopride can specifically promote intestinal motility, stimulate the intestinal tract to produce high-amplitude propulsive contraction, promote proximal colonic transit and gastric pyloric tenta Diodenal exercise can increase the frequency of bowel movements and improve the function of bowel movements, and the prokinetic effect on the colon is particularly significant. Procapride only has high affinity with 5-HT4 receptors, has no interaction with hERG potassium ion channels, and has very little interaction with other drugs. It has been approved in many countries for laxative treatment failure Female CC patients. Studies have shown that it does not cause arrhythmia even in high-risk groups, which is one of its advantages over other motility drugs.

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