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CAS:10102-18-8
Source:Europe
Qualifications:-/-/-/-/-
Name | Sodium selenite |
---|---|
Chinese name | 亚硒酸钠 |
Cas Number | 10102-18-8 |
Source | Europe |
Qualifications | -/-/-/-/- |
As an anti-cancer drug, sodium selenite is not only effective in killing cancer cells, but also less toxic to normal tissue cells. Sodium selenite is an inorganic selenium compound currently used clinically. It can be used as an adjuvant drug for cancer treatment. Studies have shown that sodium selenite can induce apoptosis in gastric cancer, colon cancer and other tumor cells. The toxic effects of different tumors require different concentrations. When a high concentration of sodium selenite acts on tumor cells, it can have a direct toxic effect on the cells and damage the cell structure. In the field of leukemia, studies have proved that sodium selenite can effectively induce apoptosis of leukemia cell line NB4 through PI3K/Akt signaling pathway. Clinical studies by researchers have found that the incidence of liver cancer is significantly negatively correlated with blood selenium levels. In low-selenium areas, supplementation of sodium selenite has effectively reduced the incidence of liver cancer in local residents. Sodium selenite can regulate various signal pathways to induce tumor cell apoptosis, which provides new ideas for the treatment of liver cancer.
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