Fluoxef Sodium API

Name	Fluoxef sodium
Chinese name	氟氧头孢钠
Cas Number	92823-03-5
Source	Korea
Qualifications	-/-/-/-/-

Fluoxef sodium was developed by Shionoyoshi Pharmaceutical Co., Ltd. of Japan. It is a broad-spectrum oxycephalosporin (xacephalosporin) antibacterial drug with similar antibacterial properties to the fourth-generation cephalosporins. Similar to other β-lactam antibiotics, fluorooxef sodium can inhibit bacterial cell wall biosynthesis by combining with one or more penicillin binding proteins (PBPs), thereby inhibiting bacterial activity. It has strong stability to β-lactamase produced by common diseases. In addition to the strong bactericidal effect of third-generation cephalosporins on gram-negative bacteria, it also has excellent anti-gram-negative bacteria activity. And it also has antibacterial activity against a variety of Gram-positive bacteria including Staphylococcus aureus methicillin-resistant strain (MRSA). Clinical pharmacology shows that the drug concentration in the prostatic fluid after the application of this drug is higher than the MIC80 value of most bacteria, which is related to its excellent efficacy. In 2017, global sales of cephalosporins were 11.86 billion U.S. dollars. In 2018, it was 12.94 billion U.S. dollars. In 2019, it will reach over 13.5 billion U.S. dollars.

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