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Active Pharmaceutical Ingredient
Tadalafil API

Tadalafil API

CAS:-
Source:India
Qualifications:USDMF/CEP/-/-/-

Product Details

Product Details

NameTadalafil
Chinese name他达拉非
Cas Number-
SynonymsTADALAFIL
ClassActive Pharmaceutical Ingredients (API) & Intermediates, API
IndustryPharmaceutical
Molecular FormulaC22H19N3O4
AppearanceWhite to Beige Powder
Molecular Weight389.4
SourceIndia
QualificationsUSDMF/CEP/-/-/-



Applications

Tadalafil is a phosphodiesterase 5 inhibitor, originally developed by GlaxoSmithKline and later jointly developed by ICOS and Eli Lillv. It was approved by the FDA in 2003 as a treatment for male erectile dysfunction (MED). ) Drugs were marketed in the United States, and later it was discovered that another clinical application of tadalafil is the treatment of pulmonary hypertension. When sexual stimulation leads to the local release of nitric oxide from the sea surface of the penis, PDE5 is inhibited by tadalafil, which increases the level of cGMP in penile blood vessels and corpus cavernosum smooth muscle cells. Tadalafil has a stronger effect on PDE5 than other phosphodiesterase enzymes. The effect of tadalafil on PDE5 is more than 10,000 times stronger than the effect on PDE1, PDE2, and PDE4 found in the heart, brain, blood vessels, liver and other organs. The effect of tadalafil on PDE5 is more than 10,000 times stronger than the effect on PDE3 found in the heart and blood vessels. Compared with similar drugs, tadalafil has the advantages of high selectivity, long half-life, and greater autonomy for patients. With these obvious advantages in efficacy, tadalafil easily ranks among the "blockbuster" drugs. Looking at the global sales data, tadalafil has already replaced sildenafil as the global ED market sales champion. The global sales of tadalafil in 2017 were US$2.3 billion, and the US market sales were US$1.359 billion. In 2019, the total sales of tadalafil, sildenafil, and vardenafil in China exceeded 3.3 billion yuan. The growth rate exceeds 8%. Among them, in public medical institutions, the market share of tadalafil has surpassed that of sildenafil.



Handle and Storage

Storage: It should be kept refrigerated between 2°C to 8°C.



Our Services

Guangzhou Tosun Pharmaceutical Limited - Business Scope



Shipping

Guangzhou Tosun Pharmaceutical Limited - Shipping

Regardless of the type of drug or the shape it takes, all products need to be handled with great care. We can offer you different shipping support from production to delivery, or anywhere in between. You can feel at ease knowing your products will be in good hands.



Company and Certificate

Guangzhou Tosun Pharmaceutical Limited - Company Profile (1)

Guangzhou Tosun Pharmaceutical Ltd. is a high-teched enterprise with modern workshops and advanced production technology, located in Guangzhou, China and with nearly 200 staff members. The construction area is more than 3,000 square meters.

With a global network of procurement, R&D and marketing, it can quickly meet the needs of domestic and foreign pharmaceutical enterprises in products of R&D, production, and marketing sales. Now, about 40% of our products are exported to foreign markets, including Europe, India, Korea, Japan, US, and so on. We have established good cooperation with customers at home and abroad.



FAQ

Q1: How to know the exact price for this product?
A: Please provide your email address and detailed order information, then we can check and reply to you with the latest and exact price.


Q2: We have more questions, how to contact you?
A: We are a renowned and authentic manufacturer and supplier of Tadalafil in China. At Tosun Pharm, we have expertise in synthetic organic chemistry and pharmaceutical analysis and we provide cost-effective and accurate custom research services to the industry. Do you want a quotation or have a question about Tadalafil? Please Enquire Now! You can send inquiries through the inquiry form below or contact us by Email or Phone/ WhatsApp directly. We normally respond within 12 hours.
Phone/ WhatsApp: +86-189-2212-0635
Email: tonghuiyy218@upharm.cn

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