Raloxifene Hydrochloride API

Name	Raloxifene Hydrochloride
Chinese name	盐酸雷洛昔芬
Cas Number	82640-04-8
Source	India
Qualifications	USDMF/-/-/-/-

Raloxifene is the first benzothiophene compound approved by the US FDA for anti-osteoporosis. It is currently widely used in the prevention and treatment of postmenopausal osteoporosis in women. Raloxifene hydrochloride belongs to the second-generation selective estrogen receptor modulators (SERMs). It has different effects on different tissues and has a two-way effect. It has an effect similar to an estrogen agonist on bone tissue and lipid metabolism. It has an anti-estrogen effect on the endometrium and breast, and is mainly used to prevent osteoporosis in postmenopausal women. Because of this tissue selectivity, the side effects or adverse reactions of this drug are significantly lower than those of estrogen when it is used in the clinical treatment of osteoporosis. Raloxifene has more advantages than tamoxifen in terms of the impact on uterine lesions, embolic events and death. Raloxifene's 2018 sales in the global market were US$200 million.

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