Trifluridine API

Name	Trifluridine
Chinese name	曲氟尿苷
Cas Number	70-00-8
Source	India
Qualifications	USDMF/-/-/-/-

Trifluridine tepipyrimidine was approved by the U.S. FDA on September 22, 2015 under the trade name Lonsurf. It has been approved for use in metastatic colorectal cancer (mCRC) in Japan, the United States, the United Kingdom, Canada, the European Union and other countries and regions. ). The results of a number of key clinical studies have shown that TAS-102 is another safe and effective treatment option for mCRC patients who are intolerant of standard chemotherapy or who develop drug resistance. At present, TAS-102 has been marketed in more than 60 countries and regions around the world, and has been recommended by multiple international authoritative guidelines: "NCCN Colorectal Cancer Clinical Practice Guidelines 2016-2019 V2 Edition" in the United States, and "ESMO Patients with Metastatic Colorectal Cancer in Europe" Management Guidelines 2016 Edition, Japan "JSCCR Colorectal Cancer Treatment Guidelines 2016 Edition, 2019 Edition", etc. On August 29, 2019, TAS-102 (trifluridine tepipyrimidine tablets) developed and produced by Japan's Dapeng Pharmaceutical Industry Co., Ltd. was officially approved by the China National Medical Products Administration

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