Bosentan API

Name	Bosentan
Chinese name	波生坦
Cas Number	147536-97-8
Source	India
Qualifications	-/-/-/-/-

Bosentan is a pulmonary hypertension drug developed by Actelion, Switzerland, and is the first endothelin receptor antagonist approved by the FDA. By reversing the contraction of the blood C tube by endothelin-1 and promoting cell proliferation, promoting vascular fibrosis and regulating other growth factors, it affects the ion channels of the smooth muscle cell membrane of the vascular wall to play its role. Bosentan can improve or maintain the WHO pulmonary hypertension functional classification of most patients, thereby delaying the time of PAH progression, improving the quality of life and overall survival rate of patients, and is an effective drug for treating primary or scleroderma-related PAH. Most experts choose Bosentan as the first-line drug for WHO III functional level idiopathic PAH and connective tissue disease-related PAH. Due to relatively few effective therapeutic drugs, the market sales of bosentan have been increasing due to the huge market demand.

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