Rasagiline Mesylate API

Name	Rasagiline mesylate
Chinese name	甲磺酸雷沙吉兰
Cas Number	161735-79-1
Source	India
Qualifications	-/-/-/-/-

Rasagiline is a second-generation monoamine oxidase inhibitor (MAO-B inhibitor), which has neuroprotection, can increase the activity of superoxide dismutase, reduce oxidative stress damage, and regulate the expression of apoptosis and anti-apoptotic genes. Increase the secretion of neurotrophic factors and protect midbrain neurons. Compared with selegiline, it has better efficacy and adverse reactions: it can significantly reduce the "switching phenomenon", improve movement disorders, and also has neuroprotective and anti-apoptotic effects. It can be used as a single agent or in combination: it has been approved for early treatment of Parkinson's alone, it can also be used in combination with levodopa for moderate to severe Parkinson's syndrome, and it can also be used in combination with dopamine receptor agonists In all periods of Parkinson's syndrome.

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