Aminolevulinic Acid Hydrochloride API

Name	Aminolevulinic acid hydrochloride
Chinese name	盐酸氨酮戊酸
Cas Number	-
Source	Europe
Qualifications	USDMF/-/-/-/-

Aminolevulinic acid hydrochloride is a precursor of hemoglobin synthesis in the body. It is a second-generation photosensitizer developed in recent years. In 2000, DUSA Corporation of the United States took the lead in developing it into a photosensitizer drug and was approved for marketing, combined with blue light for treatment Actinic keratosis. Exogenous aminolevulinic acid hydrochloride is selectively absorbed by condyloma acuminata cells and can be converted into protoporphyrin Ⅸ. The active oxygen generated under specific wavelength laser irradiation can selectively kill condyloma acuminata cells, while the surrounding normal tissue cells It is not harmed. A study conducted by several domestic authoritative organizations showed that the treatment of condyloma acuminatum with aminolevulinic acid hydrochloride can effectively reduce the recurrence rate while achieving a high cure rate. The wart clearance rate of aminolevulinic acid hydrochloride was 98.44%, the recurrence rate was 10.61%, and the recurrence rate was significantly lower than that of CO2 laser treatment (33.33%). Since the listing of aminolevulinic acid hydrochloride in 2007 to the end of 2018, it has achieved a cumulative sales of 3.374 million units and a cumulative sales revenue of more than 1.863 billion yuan.

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