Glycopyrrolate API

Name	Glycopyrrolate
Chinese name	格隆溴铵
Cas Number	58493-54-2
Source	Italy
Qualifications	USDMF/-/-/-/-

As a quaternary ammonium anticholinergic agent, Glyronium bromide can selectively act on the digestive tract, inhibit gastric juice secretion and regulate gastrointestinal motility. After taking it, it can quickly relieve spasm, suppress acid and relieve pain, and has a stronger anti-saliva secretion effect than atropine , But no central anticholinergic activity. In recent years, its single prescription and multiple compound prescriptions have been approved for the treatment of chronic pulmonary obstruction. By blocking the cholinergic receptors on the smooth muscles of the respiratory system, they can act as bronchodilators, which can relax muscles and reduce airflow limitation. Clinical studies have confirmed that Glycopyrron Bromide can take effect within 5 minutes and lasts for 24 hours. It can reduce the shortness of breath, worsening of the condition and the use of emergency drugs in patients with chronic obstructive pulmonary disease, and effectively improve lung function and quality of life. As well as improving exercise tolerance, while having good safety, it can be used for moderate to severe chronic pulmonary obstruction. Novartis's indacaterol/glycopyrrolate for the treatment of COPD was launched in China on March 16, 2019.

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