Esmolol Hydrochloride API

Name	Esmolol hydrochloride
Chinese name	盐酸艾司洛尔
Cas Number	81161-17-3
Source	India
Qualifications	USDMF/-/-/-/-

Esmolol hydrochloride is the first ultra-short-acting and selective second-generation β-receptor blocker and β1 adrenergic blocker currently used clinically, and has been widely used in the treatment room at home and abroad Upper tachyarrhythmia, acute arterial syndrome and perioperative hypertension, tachycardia, myocardial ischemia, etc. Esmolol hydrochloride mainly inhibits β1 receptors by competing for catecholamine binding sites, and has the effects of slowing down resting and exercise heart rate, lowering blood pressure and myocardial oxygen consumption. When esmolol hydrochloride produces the same β-blocking effect, it can lower blood pressure better than other selective and non-selective β-blockers such as metoprolol and propranolol. In the clinical treatment of heart failure combined with rapid atrial fibrillation with median ejection fraction, esmolol is used as a therapeutic drug to effectively improve the clinical symptoms of patients, and the application effect is more significant than that of amiodarone. In 2016, the sales of esmolol hydrochloride in sample hospitals were 83.83 million yuan, accounting for 11.3% of the beta-blocker market.

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