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Active Pharmaceutical Ingredient
Halobetasol Propionate API

Halobetasol Propionate API

CAS:66852-54-8
Source:Europe
Qualifications:/-/-/-/-

Product Details

NameHalobetasol Propionate
Chinese name卤倍他索丙酸酯
Cas Number66852-54-8
SourceEurope
Qualifications/-/-/-/-



Halobetasol propionate is synthesized by Ciba-Gergy Pharmaceutical Factory in Basel, Switzerland. It is a super strong topical corticosteroid preparation and has been widely used in the United States. The clinical pharmacological studies of halobetasol propionate show that it is a unique new corticosteroid topical drug with a slightly stronger curative effect than clobetasol. Animal experiments show that the ED50 of guinea pig ultraviolet dermatitis is 1300 and 11 times stronger than that of hydrocortisone and clobetasol, respectively. After clinical application, it was found that Halobetasol propionate was well tolerated. Only a few cases had mild side effects after topical administration, and no skin atrophy and systemic side effects were found. In clinical studies, Halobetasol propionate emulsion has shown good local tolerability, lasting up to 8 weeks of treatment without affecting the efficacy. Halobetasol Propionate Emulsion was temporarily approved by the U.S. FDA on October 12, 2018, and was finally approved on November 6, as a topical treatment drug for the treatment of plaque psoriasis in adult patients , Is an important new treatment option for psoriasis patients.




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