Tazarotene API

Name	Tazarotene
Chinese name	他扎罗汀
Cas Number	118292-40-3
Source	India
Qualifications	-/-/-/-/-

Tazarotene is the first receptor-selective, third-generation aromatic tretinoin drug. "Chinese Psoriasis Expert Consensus (2014 Edition)" recommends: glucocorticoids, vitamin D3 derivatives, tazarotene combination and sequential therapy as the first-line treatment for clinical psoriasis. As a kind of acetylene retinoic acid, tazarotene can selectively bind to the retinoic acid β receptor and γ receptor, reduce the proliferation of epidermal cells, and inhibit the differentiation related to psoriasis. Clinical comparative studies on the treatment of plaque psoriasis show that the total effective rate of tazarotene treatment is 93.94%, which is higher than the total effective rate of calcipotriol (87.87%), and tazarotene has better Maintain the efficacy of the drug. In 2016, the 18 anti-psoriatic chemical drug market in public hospitals in my country's key cities was 259 million yuan, a year-on-year increase of 43.59%. In 2014, the global psoriasis drug market sales reached 7.49 billion US dollars. Global sales of antipsoriatic drugs are expected to exceed USD 10 billion in 2019

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