Dinoprostone API

Name	Dinoprostone
Chinese name	地诺前列酮
Cas Number	363-24-6
Source	Taiwan
Qualifications	USDMF/-/-/-/-

Dinoprostone is a prostaglandin with the strongest biological activity, and is considered to be a class of drugs that promote cervical ripening. Dinoprostone slowly releases prostaglandin E2 through the control system and acts directly on the cervix via the vagina. The released collagen dissolving enzyme degrades cervical collagen fibers, softens the uterus and promotes the maturation of the uterus. At the same time, it acts on the smooth muscle of the uterus to cause contractions. The results of the study showed that compared with the use of oxytocin, using dinoprostone vaginal suppository for labor induction, the cervix of the parturient is better, the success rate of labor induction is higher, and the incidence of adverse reactions is lower. An experiment comparing the clinical effects of dinoprostone suppositories and misoprostol in the induction of labor in full-term pregnancy suggests that dinoprostone suppositories have a higher effect, which can promote maternal cervical maturation, shorten the total labor, reduce postpartum hemorrhage, and Will not increase the incidence of complications. Clinically, dinoprostone suppositories have a good effect on induction of labor for full-term women who induce labor, and have certain safety. It is a method of labor induction that is worth popularizing.

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