Nicardipine Hydrochloride API

Name	Nicardipine Hydrochloride
Chinese name	盐酸尼卡地平
Cas Number	54527-84-3
Source	India
Qualifications	USDMF/-/-/-/-

Nicardipine hydrochloride is a new type of dihydropyridine calcium antagonist. It is a cardio-cerebrovascular drug widely used in clinics at home and abroad in the 1980s. Among many calcium channel blockers, nicardipine hydrochloride has been studied for its clinical use. , With low side effects, widely used and included in the Pharmacopoeia. Nicardipine hydrochloride not only has myocardial oxygen supply, but also reduces myocardial oxygen consumption, so it can increase the exercise tolerance of patients with chronic stable angina and reduce the frequency of angina pectoris. The hypotensive effect of nicardipine hydrochloride is to dilate small arteries and reduce total peripheral vascular resistance, without affecting sympathetic nerve activity. Domestic clinical studies have proved that nicardipine hydrochloride and sodium nitroprusside have significant relief in the treatment of hypertensive emergencies, but the overall effect of nicardipine hydrochloride is better than sodium nitroprusside, and the heart rate of nicardipine hydrochloride is better. Another study pointed out that in general anesthesia for orthopedic surgery in elderly patients, the combined application of nicardipine hydrochloride and dexmedetomidine can effectively maintain the stability of hemodynamics, and can improve the clarity of the surgical field, reduce the operation time, and reduce the controllability. The pressure effect is ideal. QYResearch data predicts that by 2022, the global market for antihypertensive drugs will reach 35 billion U.S. dollars.

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