Emestine API

Name	Emestine
Chinese name	依美斯汀
Cas Number	87233-61-2
Source	Europe
Qualifications	-/-/-/-/-

Emestine is an ophthalmic drug developed by Alcon to relieve allergic conjunctivitis. Emestine has a strong and selective antihistamine effect. It can also be found in experimental allergic models that it has obvious anti-allergic effect, inhibition of nasal respiratory resistance rise, and inhibition of eosinophil infiltration into the nasal mucosa. In addition, Emestine also has an inhibitory effect on the release of histamine from mast cells caused by substance P stimulation in vitro, and an inhibitory effect on the migration of eosinophils caused by platelet activation factor and leukotriene B4. Compared with similar drugs, Emestine has the characteristics of high curative effect, less side effects, good tolerance, no cardiotoxicity, etc., especially for central sedation, no side effects such as drowsiness after use, so it is very popular among patients. . Another experimental study found that Emestine sustained-release capsules are effective in treating chronic urticaria, and the effective rate is equivalent to that of loratadine tablets. In 2018, the sales of systemic anti-allergic drugs (mainly antihistamines) in China exceeded 5 billion yuan, a year-on-year increase of 5.1%. Among them, the amount of antihistamines used in public hospitals in key cities in China reached 476 million yuan, an increase of 13.72% year-on-year.

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