Buspirone API

Name	Buspirone
Chinese name	丁螺环酮
Cas Number	36505-84-7
Source	India
Qualifications	USDMF/-/-/-/-

Buspirone is a new generation of non-BZ anti-anxiety drugs with anti-anxiety effects, but its mechanism of action is different from benzodiazepines. It mainly acts on 5HT1A receptors and dopamine receptors in the hippocampus to make serotonin The function is down-regulated to produce anxiolytic effects. It is a highly selective anti-anxiety drug. Aripiprazole combined with buspirone has a significant clinical effect in the treatment of patients with schizophrenia, and can effectively improve patients' positive symptoms, negative symptoms and cognitive dysfunction. Compared with aripiprazole treatment alone, it has higher safety and is worthy of application and promotion. In 2017, the sales of buspirone tablets in the three terminal public hospitals of cities, counties and towns in my country were approximately 130 million yuan. According to IMS statistics, the total sales of buspirone hydrochloride tablets in the US market from March 2018 to March 2019 was approximately US$88 million.

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