Ziprasidone Mesylate API

Name	Ziprasidone Mesylate
Chinese name	甲磺酸齐拉西酮
Cas Number	199191-69-0
Source	United States
Qualifications	USDMF/-/-/-/-

Ziprasidone mesylate is a new atypical broad-spectrum antipsychotic developed by Pfizer for the treatment of schizophrenia. This product is a serotonin and dopamine receptor antagonist, especially for 5-HTA2/DA D2 Strong receptor affinity. It was listed in Sweden for the first time in September 2000, and entered the Chinese market in 2007. It is now listed in more than 50 countries in the world. Ziprasidone mesylate is effective for both positive and negative symptoms of schizophrenia, and is especially effective for negative symptoms and has high safety. Compared with traditional antipsychotics, the drug not only improves positive and negative symptoms, but also improves cognitive function and significantly improves tolerance. Ziprasidone hydrochloride tablets are suitable for short-term and long-term treatment, while ziprasidone mesylate injection is used for the acute treatment of schizophrenia and the clinical treatment of agitated patients with schizophrenia who are not convenient for oral medication. Compared with the widely used olanzapine, quetiapine, risperidone, etc., this product has a better or equivalent effect on negative symptoms, does not cause weight gain and increased serum prolactin levels, and has less side effects than existing atypical anti Psychiatric drugs. Ziprasidone injection is a milestone leap. With the increase in the frequency of clinical use of ziprasidone in China, we will have a deeper understanding and understanding of its reliability and efficacy.

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