Gadolinium Diamine API

Name	Gadolinium Diamine
Chinese name	钆双胺
Cas Number	131410-48-5
Source	Taiwan
Qualifications	-/-/-/-/-

Gadolinium diamine is a non-ionic paramagnetic water-soluble contrast agent developed by GE Healthcare. After injection, gadolinium diamine is quickly distributed to the extracellular fluid, and its distribution is equal to the amount of water in the extracellular fluid. The non-ionic contrast agent gadolinium diamine is a new generation product that is safer than ionic magnetic resonance contrast agents (such as gadopentetate meglumine). Its non-ionic structure significantly reduces the number of particles in the solution and penetrates into body fluids. The impact of pressure balance is very small. At the same time, the relatively low viscosity of gadolinium diamine brings convenience to nursing staff and makes it easier to inject. In addition, Gadolinium Diamine pioneered the use of amide groups to replace part of the carboxyl groups, which not only reduces the toxicity of the carboxyl groups but also ensures that the product is a non-ionic solution. In 2018, the sales of terminal gadolinium diamine injections in public medical institutions in China was 350 million yuan, a year-on-year increase of 15.94%. In 2019, the sales of terminal contrast agents in urban public hospitals, county-level public hospitals, urban community centers, and township health centers in China were 15.210 billion yuan, a year-on-year increase of 10.36%.

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