Roxatidine Acetate API

Name	Roxatidine Acetate
Chinese name	罗沙替丁醋酸酯
Cas Number	78628-28-1
Source	Korea
Qualifications	-/-/-/-/-

Roxatidine is a fourth-generation H2 receptor antagonist (H2RA), a long-acting H2RA, has stronger acid inhibitory effect than ranitidine, and has a mucosal protective effect. Roxatidine can effectively inhibit the secretion of gastric acid caused by histamine, pentagastrin and carbachol stimulation, and reduce gastric acid and gastric enzyme activity. It is mainly used for the treatment of hyperacidity and heartburn. There are clinical data It shows that in the comparison of H2 receptor antagonist treatment of peptic ulcer recurrence rate, rosatidine is the smallest. Compared with cimetidine, rosatidine acetate does not affect the function of liver microsomal oxidase. It has no anti-androgen-like effect and does not interfere with the metabolism of other drugs in the liver. It has been listed in 9 countries including South Korea, Germany, France, Sweden, Switzerland, and Italy. The injections that have been approved for marketing in Japan are mainly used for the treatment of gastrointestinal bleeding. At present, there are few drugs used clinically to treat gastrointestinal bleeding. The most commonly used are Ranitidine Hydrochloride, Omeprazole, and Pantoprazole Injection. Ranitidine has definite curative effect but many side effects and the cost of proton pump treatment is too high. In summary, this product has huge market potential in the future and sales expectations are good.

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