Ulinastatin API

Name	Ulinastatin
Chinese name	乌司他丁
Cas Number	80449-31-6
Source	Europe
Qualifications	-/-/-/-/-

Ulinastatin (UTI) is a protease inhibitor extracted from human urine. It is a broad-spectrum protease inhibitor and belongs to human endogenous anti-inflammatory substances. It has two active functional areas, a wide inhibitory spectrum, stabilizes the lysosomal membrane and inhibits the release of hydrolytic enzymes in the lysosome, inhibits the production of myocardial inhibitors, reduces the production of oxygen free radicals, and inhibits excessive inflammation mediators The role of release. Under normal conditions, the human body contains a large amount of UTI. UTI has a protective effect on important organs such as the heart, liver, lung, and kidney. It has strong anti-inflammatory effects, reduces cell and tissue damage, improves microcirculation, and improves tissue perfusion. . UTI is currently one of the main drugs for clinical treatment of acute pancreatitis. Studies have found that early application of UTI in the treatment of patients with acute and chronic recurrent pancreatitis has a significant effect, with rapid relief of symptoms and signs, and fewer adverse reactions, which significantly improves the prognosis of patients. Related guidelines recommend that this product be used in sufficient quantities in the early stages of acute pancreatitis, and the clinical prospects are good.

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