Metoclopramide Hydrochloride API

Name	Metoclopramide hydrochloride
Chinese name	盐酸甲氧氯普胺
Cas Number	54143-57-6
Source	Europe
Qualifications	/CEP/-/-/-

This product is a dopamine 2 (D2) receptor antagonist, and it also has 5-tibiotryptamine 4 (5-HT4) receptor agonistic effects, and has a light charge inhibitory effect on 5-HT3 receptors. It can act on dopamine receptors in the chemosensory zone of the medulla oblongata (CTZ) to increase the threshold of CTZ, and has a powerful central antiemetic effect. This product can also block dopamine receptors in the hypothalamus, inhibit prolactin inhibitors, and promote the secretion of prolactin, so it has a certain prolactin effect. It has less inhibitory effect on other parts of the central nervous system, has a weaker stabilizing effect, and less causes hypnotic effects. It can be used for chemotherapy, radiotherapy, surgery, craniocerebral injury, sequelae of brain injury, naval operations and drug-induced vomiting; it can also be used for the symptomatic treatment of nausea and vomiting symptoms of various diseases such as acute gastroenteritis, biliary pancreas, and urinary symptom ; It can also be used before diagnostic duodenal intubation to help smooth intubation; gastrointestinal barium X-ray examination can reduce nausea and vomiting; promote the passage of barium.

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