Nifuratel API

Name	Nifuratel
Chinese name	硝呋太尔
Cas Number	4936-47-4
Source	Europe
Qualifications	/CEP/-/-/-

Nifuratel is used to treat mixed gynecological infections, and it is also the only medicine approved by the SFDA to treat gynecological infections that can be safely used by pregnant women. At present, the most commonly used drug in clinical practice is metronidazole. Metronidazole has a good effect on trichomonas and anaerobic infections. However, metronidazole can easily enter the fetus through the placenta, causing cancer in animals and bacteria. Mutation effect, and Nifuratel mainly inhibits the growth of bacteria by interfering with the enzyme system, it is difficult to penetrate the placenta, and has no teratogenic effect. Oral and vaginal administration of nifuratel shows that it is well tolerated and has no drug resistance. The cure rate for bacterial vaginitis is equivalent to ampicillin and carbenicillin, and the incidence of adverse reactions is significantly lower than that of ampicillin , Carbenicillin. In 2016, the total amount of external use of nifuratel nystatin in public hospitals in major cities in China reached 54.36 million yuan, becoming the first variety of anti-infective external drugs for gynecology in public hospitals in key cities, a year-on-year increase of 2.74 %.

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