Sunitinib Malate API

Name	Sunitinib malate
Chinese name	苹果酸舒尼替尼
Cas Number	341031-54-7
Source	India
Qualifications	USDMF/-/-/-/-

Sunitinib malate capsules (hereinafter referred to as sunitinib) is a small molecule multi-target receptor tyrosine kinase (RTKs) inhibitor, which has multiple effects of inhibiting tumor angiogenesis and anti-tumor cell production and metastasis , The targets include: PDGFR (PDGFRα and PDGFRβ), VEGFR (VEGFR1, VEGFR2, VEGFR3), FLT-3, CSF-1R, kit and ret. It is mainly used clinically to treat gastrointestinal stromal tumors, renal cell carcinoma and Adult patients with pancreatic neuroendocrine tumors, the original research company is Pfizer, the trade name is Sunitinib, it was approved by the US FDA in January 2006, and it was approved for listing in the EU in June of the same year, and it was approved to enter the Chinese market in 2007. The Chinese trade name is Suo Tan.

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