Homatropine Hydrobromide API

Name	Homatropine hydrobromide
Chinese name	氢溴酸后马托品
Cas Number	51-56-9
Source	India
Qualifications	-/-/-/-/-

Homatropine hydrobromide is the phenylglycolic ester of atropine, which is an anticholinergic drug that blocks acetylcholine. Homatropine hydrobromide paralyzes the pupillary sphincter and ciliary muscles, causing mydriasis and paralysis of accommodation. The pharmacological effects of homatropine hydrobromic acid are similar to that of atropine. Its toxicity is weaker than that of atropine. Its ability to block cholinergic nerves is only 1/10 of that of atropine, and its mydriatic effect is faster than atropine, and its maintenance time is shorter. , It can be recovered within 1 to 2 days, and it is more convenient for eye examination and optometry. Animal experiments pointed out that compared with the pharmacodynamics of eye drops, the post-matropine hydrobromic acid in situ gel is safe, non-irritating to the eyes, reduces the number of administrations, and improves patient compliance It also prolongs the retention time of the drug in the eye and improves the bioavailability of the drug. Therefore, homomatropine hydrobromide has very good application value and is worthy of clinical promotion.

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