Amorolfine Hydrochloride API

Name	Amorolfine Hydrochloride
Chinese name	盐酸阿莫罗芬
Cas Number	78613-38-4
Source	Italy
Qualifications	USDMF/-/-/-/-

Amorolfine hydrochloride is an antifungal drug developed by Roche and listed in 1991 under the trade name Leceryl. Amorolfine is a representative drug of the fifth class of morpholine antibacterial drugs. By inhibiting the reductase and isomerase required for the conversion of hypoergosteroids into ergosterols, it promotes the accumulation of hypoergosteroids and greatly reduces ergosteroids. It damages the structure and function of fungal cell membrane, and has the effect of inhibiting and killing fungi. This product has high in vitro activity, has a good therapeutic effect on superficial fungal infections, can effectively inhibit onychomycosis caused by skin mosses, and is particularly sensitive to skin mosses. Compared with allylamine drugs, the antibacterial activity of dermatophytes is comparable, but higher than that of azole drugs. Compared with echinocandin drugs, it has a more affordable price, a wider antibacterial spectrum and a broad market prospect. .

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