Dutasteride API

Name	Dutasteride
Chinese name	度他雄胺
Cas Number	164656-23-9
Source	Italy
Qualifications	USDMF/-/-/-/-

This product is mainly used for the treatment of patients with benign prostatic hyperplasia. It can improve the symptoms of BPH for a long time. It can also reduce the incidence of prostate cancer. 5α reductase is an important reason for the continuous progress of benign prostatic hyperplasia disease. It can promote the conversion of testosterone in the patient's prostate to the more active dihydrotestosterone, which leads to the proliferation of prostate cells and the hypertrophy of the prostate. Therefore, the key to the treatment of benign prostatic hyperplasia is to inhibit 5α reductase. Dutasteride can inhibit both type I and type II 5α reductase. Through this'dual inhibition' mechanism, dutasteride can rapidly and continuously shrink Prostate volume can significantly improve lower urinary tract symptoms, reduce acute urinary retention and related risks of prostate surgery, and provide long-lasting benefits for patients, especially patients with moderate to severe benign prostatic hyperplasia. Compared with traditional finasteride, dutasteride has a more effective inhibitory effect on serum DHT, with a low incidence of adverse events and relatively low overall medical costs.

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