Cinacalcet Hydrochloride API

Name	Cinacalcet Hydrochloride
Chinese name	盐酸西那卡塞
Cas Number	364782-34-3
Source	India
Qualifications	USDMF/-/-/-/-

Cinacalcet is the first drug in a new class of compounds called calcimimetics. It was approved by the FDA in 2004. It can activate calcium receptors in the parathyroid glands, thereby reducing parathyroid hormone ( PTH) secretion. It is used to treat secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) undergoing dialysis, and hypercalcemia in patients with parathyroid cancer. In 2018, Cinacalcet’s sales in the United States were $1.43 billion. Cinacalcet hydrochloride is currently the only calcimimetic listed in China. It was launched in China in February 2015 and was approved for the treatment of "maintenance dialysis patients with SHPT". With the expiration of the patent, Chinese pharmaceutical companies have accelerated The pace of listing of generic drugs.

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